Significance of Preclinical Studies in Drug Development
The drug discovery process starts with finding a promising chemical compound that can be used as a therapeutic agent against the desired target. Preclinical development solutions include an endless array of experiments as it requires study and research to be done on a large number of reactions and bonds between tiny chemical blocks and the human body.
Researchers and scientists working in a Drug Discovery CRO need to have the apt knowledge and skills in drug discovery chemistry services along with biology to discover improved solutions for the known problems and develop novel answers for new challenges with minimal adverse effects. Here, we’ll further explain the significance of preclinical research in drug development.
What Preclinical Research Includes?
As the term “preclinical studies” itself is suggesting, it encompasses various processes that are required for the initial stages of drug development. It can be easily called the first stage of the drug discovery services and is a vital part of the phenomena of finding new cures and potential treatments for both novel and already known diseases.
The major stages of preclinical drug development are as mentioned below:
- Target Identification: It is the process of identifying the direct molecular target, which is usually a protein or nucleic acid of a small molecule.
- Lead Identification: In this process, “hits” are transformed into “leads” through extensive screening processes.
- Efficacy and Safety: As the initial target is determined and lead is identified, preclinical services are needed to decode the levels of toxicity, efficacy, and safety of the new drug.
Benefits of Preclinical Development Solution
Drug development can not be considered complete without preclinical research as it serves incredible objectives. Preclinical studies represent one of the most important stages in all of Drug Discovery as the first interaction with living biological systems. The major benefits of it are as mentioned below.
- Drug discovery chemistry services aid CROs to understand how the chemistry behind the corresponding therapeutic agent affects the biological system.
- It allows scientists to fully understand the complex interactions between the new drug and living systems and their ultimate effect as therapeutic agents.
- Preclinical development solutions deal with testing a new drug compound in measurable ways to understand how it functions in real-time while creating useful insights for a clearer understanding of all biological reactions.
With the end goal being entering clinical trials and testing on human subjects, these initial tests preclinical development solutions significantly drive the course of drug development. Any study on humans can only be approved if the new potential drug compound is tested and understood as much as possible as a therapeutic agent.
Everything that could affect humans needs to be understood comprehensively. Researchers and scientists at a drug discovery contract research organization not only need to anticipate the reaction but also to understand the bonds and reactions that are going to happen eventually. Only after achieving a credible level of reliability, a new drug can be tested on animals that significantly replicates human biology.
Get The Best Preclinical Drug Development Solutions From Integral Biosciences
From preclinical stages of Drug Discovery to later stages, it is all about understanding the new treatment concerning how it affects and reacts with biological systems, that is, humans. Collaborate with Integral Biosciences to acquire the best in class preclinical development solutions.
IBS has a tremendous team of chemistry and biology experts and is equipped with the latest tools and technology for delivering brilliant drug discovery chemistry services along with biological services. Connect with the experts at Integral Biosciences today and accelerate your drug discovery projects towards promising results.
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