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You have plants that have very high levels of thc these days as opposed to maybe 20 or 30 years ago thc concentrations in plants for anywhere from one to three percent now you can have thc concentrations as high as 25 or more and that’s been through cultivation hemp cream to select for the enzymes that preferentially will produce delta nine thc from these precursors and produce less cbd and in general there’s a bit of a yin yang where plants that produce a lot of thc will produce less cbd.
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Whereas plants that produce a lot of cbd generally have low amounts of thc okay thanks and and you said that uh that they act in the brain so um why do they act in the brain these are you know components of plants so maybe you and ziva could take a shot at that sure i can start and then i’ll hand it off to ziva but i i like to think of this as an uh a good analogy is thinking about um opioids so clearly there are opiates that are derived from plants opium poppies produce molecules that act on the human brain to produce a variety of effects the brain also produces endogenous opioid peptides like endorphins that are released during pleasurable activities and things like that both of those compounds act at the brain on opioid receptors and the same.
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Is true for cannabinoids so the thc produced by cannabis plants acts at a cannabinoid type 1 and 2 receptor within the brain and peripheral organs of humans and most other mammals um there are also these endogenously produced cannabinoids that also act at that same type 1 and type 2 cannabinoid receptor in the brain so the body and the brain have these receptors as part of a normal physiological function it just happens that this molecule produced by cannabis plants also interacts with this receptor quite well and when people ingest it or take it in some way it exerts a lot of effects um through the brain and body by interacting with this particular receptor a cannabinoid type one and two receptors okay xev you wanted to comment on that yeah that was a great introduction i also want to add that what we’re seeing in places where medical and non-medical use have been legalized or regulated is a interest beyond just the delta 9 hemp pain relief cream uk and cbd we’re also seeing a lot of interest in some of these other minor cannabinoids that dr patel hit on um for example cannabigirl cbg cbn delta 8 thc which we’ll talk about and then there are also chemicals in the cannabis plant that are shared with other plants and these are called terpenes terpenes provide the smell and the taste of cannabis as well as other herbs and fruits and vegetables and some people think that these terpenes also produce biological effects that might be therapeutic and what’s interesting is that a lot of people think that even though these chemicals are you know they’re produced.