Impact of the use of Maitake mushroom extract in cancer patients with myelodysplastic syndromes
A phase II clinical study conducted by researchers at Memorial Sloan Kettering Cancer Center Integrative Medicine Service in the US evaluated the effects of supplementing Maitake mushroom extract (3 mg/kg) for 12 weeks on immune function innate in 18 myelodysplastic syndromes (fantasy shrooms). ) patients.
The study found that Maitake mushroom extract was well tolerated in these cancer patients and also increased basal neutrophil and monocyte function in vitro, suggesting the immunomodulatory potential of Maitake mushroom extract in MDS. (Kathleen M Wesa et al, Cancer Immunol Immunother., 2015)
Impact of Maitake mushroom polysaccharide on breast cancer patients
En un ensayo clínico de fase I / II realizado por los investigadores del Servicio de Medicina Integrativa del Centro Oncológico Memorial Sloan Kettering de EE. UU., Evaluaron los efectos inmunológicos del polisacárido del hongo Maitake en 34 pacientes posmenopáusicas con cáncer de mama que estaban libres de la enfermedad después del tratamiento inicial. . Los pacientes recibieron 0.1, 0.5, 1.5, 3 o 5 mg / kg de extracto de hongo maitake oral dos veces al día durante 3 semanas. (Gary Deng y col., J Cancer Res Clin Oncol., 2009)
The study found that oral administration of maitake mushroom polysaccharide extract was associated with immunologically stimulating and inhibitory effects on peripheral blood. While increasing doses of Maitake mushroom extracts increased some immunological parameters, it depressed others. Therefore, the researchers stressed that cancer patients should be made aware of the fact that Maitake mushroom extracts have complex effects that can depress and enhance immune function at different concentrations.
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