Guide to CAS NO: 85118-00-9 Manufacturers — Overview
CAS NO: 85118-00-9 refers to 2,6-Difluorobenzyl bromide, a versatile organic chemical intermediate widely used in the pharmaceutical, specialty, and fine chemical industries. If you're seeking comprehensive insights on this compound and its manufacturing landscape (with no specific company endorsement), this blog will serve as your technical resource.
What is 2,6-Difluorobenzyl Bromide?
- Chemical Formula: C7H5BrF2
- Molecular Weight: 207.02
- Structure: Contains a benzyl bromide functional group substituted at the 2 and 6 positions with fluorine atoms.
- Synonyms: α-bromo-2,6-difluorotoluene, 2,6-DIFLUOROBENZYL BROMIDE.
- Physical Form: Typically supplied as a clear to pale yellow liquid.
Applications & Uses
2,6-Difluorobenzyl bromide (CAS NO: 85118-00-9) is primarily used as a chemical intermediate, particularly for:
- Pharmaceutical Synthesis: An intermediate in the preparation of active pharmaceutical ingredients (APIs), such as Relugolix (a GnRH antagonist) and Rufinamide (an antiepileptic agent).
- Specialty Chemistry: Used as a reagent in alkylation reactions and the synthesis of heterocycles like quinazolines and triazines.
- Research & Development: Employed for various organic transformations and custom molecule synthesis in laboratories.
Manufacturing Overview
Manufacturers of CAS NO: 85118-00-9 generally follow these standard production and quality steps:
- Raw Material Selection: Sourcing of high-purity starting compounds and reagents.
- Synthesis: Bromomethylation of difluorotoluene in controlled environments to ensure selectivity and yield.
- Purification: Use of distillation and chromatographic methods to achieve required purity levels (often >98%).
- Quality Assurance: Strict profiling using spectroscopic techniques like NMR and HPLC.
- Packaging & Storage: Delivered in moisture-proof containers. Recommended storage is cool, dry, and under inert gas for stability.
Key Features & Specifications
Parameter
Description
CAS Number
85118-00-9
Chemical Name
2,6-Difluorobenzyl bromide
Molecular Formula
C7H5BrF2
Purity
≥98% (Typical)
Applications
Pharma, R&D, Synthesis
Storage
Cool, dry place; inert atmosphere
Regulatory and Safety
- Hazards: Like most benzyl bromides, may cause skin and eye irritation; handle with gloves and protective equipment.
- MSDS Available: Manufacturers provide Material Safety Data Sheets detailing safe handling and disposal guidelines.
How to Source CAS NO: 85118-00-9
If you're looking for manufacturers:
- Focus on firms following international standards (ISO/ GMP).
- Look for those offering batch customization, document support (COA, MSDS), and reliable logistics.
- Compare specifications and regulatory compliance, not just pricing.
Summary
2,6-Difluorobenzyl bromide (CAS NO: 85118-00-9) is a widely produced specialty chemical essential for advanced synthetic applications. When evaluating its manufacturers, prioritize quality, safety, purity, and technical support while ensuring global regulatory standards are met. This approach secures successful procurement for research and industrial needs—without preference for any specific brand or company
URL: For more information, visit Vasista Pharma: CAS NO: 85118-00-9 Manufacturers