When consuming CBD levels as little as 25 mg, those who have trouble sleeping due to anxiety, depression, pain, or stress may notice improvements in their sleep. Adults in good health may need significantly greater doses (300 to 600 mg per day). How does taking CBD oil before bed affect me? Your body can become less stressed and more relaxed by taking the right dosage of Best CBD Tincture For Sleep 30 to 60 minutes before bed. This may help you fall asleep more quickly and possibly enhance the overall quality of your sleep.